Little Sarasota Bay, covering 1,828 acres, is a bay situated in Sarasota County, with the associated WBID(s): 1968E.

This slender bay is central to the communities of Sarasota, Osprey, Siesta Key and Casey Key. Native people populated the area from at least 4000 years ago. The first settlers, the Webb family, built Spanish Point in 1847 and farmed there for decades. In 1983, the former Midnight Pass was closed, which reduced tidal flushing and changed the ecosystem of the bay. Midnight Pass naturally reopened in late 2024 after Hurricanes Helene and Milton. Several creeks discharge to the bay, including Matheny Creek, Elligraw Bayou, Holiday Bayou, Clower Creek, Catfish Creek, and North Creek. The bay is within the Sarasota Bay Estuary Program study area and is protected by designation as an Outstanding Florida Water. It is also one of SWFWMD's Surface Water Improvement and Management (SWIM) waterbodies.

For additional information on Midnight Pass, visit Sarasota County's Midnight Pass Webpage, which includes a cross-section interactive dashboard and weekly survey results.